09/02/2026
Feeling like your body is constantly stuck in stress mode? One reason may be prolonged activation of your stress-response system — and this is where ashwagandha has been getting attention.
Ashwagandha is an adaptogenic herb, meaning it may help the body adapt to physical and psychological stress. Research suggests it may influence the HPA axis (hypothalamic-pituitary-adrenal axis) — the system responsible for regulating your body's stress response and cortisol production.
How could it help?
✨ May support healthier cortisol levels
Several randomized controlled trials have found that people taking ashwagandha experienced reductions in cortisol compared with placebo, particularly after several weeks of consistent use.
✨ May help with perceived stress
Studies have also reported improvements in measures of perceived stress and anxiety in some participants.
✨ Works gradually
Ashwagandha isn't an instant "cortisol blocker." Its potential effects appear to develop with consistent use over several weeks.
✨ Withanolides are the key compounds
Ashwagandha contains naturally occurring compounds called withanolides, which are believed to contribute to many of the plant's biological effects.
A few important precautions
Ashwagandha is natural — but natural doesn't automatically mean risk-free.
⚠️ It may interact with certain medications, including medications for thyroid disorders, blood sugar, blood pressure, immune suppression and sedatives.
⚠️ Ashwagandha may affect thyroid hormone levels, so people with thyroid conditions should speak with their healthcare professional before using it.
⚠️ It may cause side effects such as stomach upset, diarrhea, nausea or drowsiness in some people.
⚠️ Pregnant or breastfeeding? It's generally recommended to avoid ashwagandha unless specifically advised by a qualified healthcare professional.
⚠️ People with certain autoimmune or liver conditions should consult a healthcare professional before taking it. Rare cases of liver injury have been reported.
The bottom line
Research is promising that ashwagandha may help support the body's response to stress and reduce cortisol levels in some people.
